Muscle mass can decline.
Fatigue can increase.
And everyday activities may become harder.
The good news is that muscle health is not necessarily something people with kidney disease must simply accept as lost.
Appropriate exercise, adequate nutrition, treatment of kidney disease and management of complications can all play a role in preserving physical function.
## Final Thoughts
Your kidneys and muscles may seem like completely separate parts of the body, but they are deeply connected.
Muscles depend on stable levels of water and electrolytes.
They require oxygen and nutrients.
They depend on proper calcium and phosphate regulation.
They generate metabolic waste that the kidneys help eliminate.
And they function best when the body’s acid-base and hormonal systems remain balanced.
The kidneys help maintain many of those conditions.
When kidney function declines, muscle health can suffer as a