and bone disorders associated with chronic kidney disease.
The body may respond by changing levels of parathyroid hormone and vitamin D metabolism.
Over time, this can affect bones and potentially contribute to weakness and other physical problems.
Again, the kidney-muscle relationship is interconnected.
Kidneys regulate minerals.
Minerals influence bones and muscles.
Hormones respond to mineral changes.
And the entire system interacts with nutrition and physical activity.
## Vitamin D and the Kidneys
Vitamin D has several important roles in the body, including effects on calcium and bone metabolism.
The kidneys participate in converting vitamin D into its biologically active form.
When kidney function is impaired, this process can be disrupted.
The resulting changes in calcium, phosphate and parathyroid hormone can contribute to chronic kidney disease-mineral and bone disorder.
Because of this complex system, people with kidney disease should
